Sildenafil is actually a potent and selective inhibitor of cGMP-specific phosphodiesterase form 5 (PDE5), that's to blame for degradation of cGMP inside the corpus cavernosum. The molecular structure of sildenafil is analogous to that of cGMP and acts as a aggressive binding agent of PDE5 inside the corpus cavernosum, leading to additional cGMP and… Read More